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Phase I Safety Profile: While topical and low-dose injectable formulations demonstrate high tolerance and minimal systemic toxicity, there is no formal Phase I safety data for chronic 85 mg/day intranasal delivery in humans

Dermal papilla cells are important cells at the base of the hair follicle

Jeong S-H, Jang J-H, Cho H-Y, Lee Y-B (2021) Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Overexpression of platelet-derived growth factor B enhances expression of pro-oncogenic factors, including -catenin, VEGF, and platelet endothelial cell adhesion molecule-1 82