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It comes from the amino acid L-cysteine, which helps produce glutathione

Abbreviations AGE: Advanced glycation end product AMD: Age-related macular degeneration AR: Aldose reductase ATM: Ataxia-telangiectasia mutated CMA: Chaperone-mediated autophagy FoxO3: Forkhead box O-3 HIF-1 : Hypoxia-inducible factor-1 HOPS: Homotypic fusion and protein sorting IOP: Intraocular pressure KEAP1: Kelch-like ECH-associated protein 1 LIR: LC3-interacting region mTORC1: Mechanistic target of rapamycin complex 1 NPDR: Nonproliferative diabetic retinopathy NQO1: NADPH quinone dehydrogenase 1 NRF2: Nuclear factor erythroid 2related factor 2 ONC: Optic nerve crush ONL: Outer nuclear layer PAS: Pre-autophagosomal structure PDR: Proliferative diabetic retinopathy PI3K: Phosphatidylinositol 3 kinase PI3P: Phosphatidylinositol 3-phosphate PINK1: PTEN-putative kinase 1 POAG: Primary open angle glaucoma POSs: Photoreceptor outer segments RGC: Retinal ganglion cell RPE: Retinal pigmented epithelial ROCK1: Rho-associated coiled-coil-containing protein kinase 1 ROS: Reactive oxygen species SOD: Superoxide dismutase TFEB: Transcription Factor EB TM: Trabecular meshwork UBA: Ubiquitin-associated UVRAG: UV radiation resistance-associated VEGFA: Vascular endothelial growth factor A References De Duve C, Wattiaux R

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Channing, C.P., et al., Ovarian follicular and luteal physiology, in International Review of Physiology, R.O