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This phenomenon could be further exacerbated by the depletion of the methyl donor S-adenosylmethionine (SAM) pool, as a consequence of VitB12 deficiency, a universal methyl donor needed for the methylation of DNA, RNA, proteins, neurotransmitters, and phospholipids
Mutations in ATP2A2 , encoding a Ca 2+ pump, cause Darier disease
Miranda-Loureno C, Ribeiro-Rodrigues L, Fonseca-Gomes J, Tanqueiro SR, Belo RF, Ferreira CB, Rei N, Ferreira-Manso M et al (2020) Challenges of BDNF-based therapies: from common to rare diseases
