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13 Inflammation mediated by immune cells was enhanced in degenerated IVDs, and degradation products of these cells, such as IL-4, IL-6, IL-12, IFN-, and MMPs, led to a reduction in NP cell number and deterioration of the IVD microenvironment

A company that identifies a patent weakness two years before its competitors and prepares a Paragraph IV filing stands to gain a multi-year head start

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