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Effects of Dopamine on the Glutathione Metabolism of Cultured Astroglial Cells: Implications for Parkinson's Disease. Journal of Neurochemistry 82: 458467

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NO generated in endothelial cells diffuses rapidly to adjacent smooth muscle cells, which activates soluble guanylate cyclase (sGC) and allows the conversion of GTP to cyclic GMP, initiating a signaling cascade leading to vasodilation [8, 9]