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Since the renal clearance , soClR=(dDu/dt)/CPClR.CP=dDu/dt Rearranging and integration of the last equation will give: If a graph were plotted of the cumulative drug excreted in the urine versus the area under the plasma-level time curve, renal clearance is the slope of the curve
Front Cardiovasc Med 2022
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Xiang L, Xie G, Liu C, Zhou J, Chen J, Yu S, Li J, Pang X, Shi H, Liang H
