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IGF and IGFBP Daughaday et al

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In contrast, Perilipin family protein 1 (PLIN1) works with the mitochondrial fusion protein MFN2 to form an alternative contact interface that directs lipid droplet-derived fatty acids to mitochondria for energy production [201]

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Complementary mechanisms

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The activation of immune-regulatory cells by WS extracts may serve multiple purposes, including modulation of antigen presentation, regulation of the immunosuppressive tumor microenvironment, and maintenance of a balanced cytokine profile that supports effective T cell responses [59]

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