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For instance, agents classified as carcinogenic via inhalation may not exert similar effects when ingested, and epidemiological associations involving organs not typically targeted by a compound may signal confounding rather than true causation [300]

Santomasso, B

doi: 10.1016/j.addr.2013.08.008 153 El OuaamariYVan den BosJWillekensBCoolsNWensI

Beyond direct antimicrobial activity, metal ions can reprogram the dysregulated immune microenvironment, modulating macrophage polarization, reducing inflammation, and supporting tissue integration 209
