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Conditions such as neurodegenerative disorders, cancer, and liver diseases such as NAFLD have been closely linked to GSH homeostasis disruptions [29,83,87]
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia
One of these by-products is malondialdehyde (MDA)
120 Additionally, the transcription of MT1/2 genes is governed by MTF-1, a zinc finger transcription factor that regulates the expression of metal-responsive genes
