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However, these benefits are more plausibly interpreted as downstream consequences of improved metabolic and inflammatory milieus, rather than as effects directly targeting uric acid metabolism.In addition, these medications can cause adverse reactions such as water and sodium retention and weight gain, necessitating careful consideration of the patients cardiac function status
10.1146/annurev.arplant.47.1.127 105 MarshM.ShoemarkD

however, the conversion of glucoraphanin to sulforaphane still occurs in mammals
