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However, CF, PCD, and NCFB are rarer with incidences ranging from 1 in 20,000 for PCD, between 50 and 1,000 in 100,000 for NCFB, and around 160,000 individuals with CF worldwide (Nigro et al., 2024
[2] [309] [310] [311] [312] It is under evaluation in Australia
Being precise about these is the difference between reading the literature accurately and being misled by it
Conformational change in the ligand-binding domain has been a basic requirement for the construction of FRET-based nanosensors, and also for translating metabolite binding into a change in FRET 26
