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Maintaining an adequate GSH redox status and 25-hydroxy-vitamin D levels will have the potential to reduce oxidative stress, enhance immunity and diminish the adverse clinical consequences of COVID-19 especially in African American communities having glucose-6-phosphate dehydrogenase (G6PD) deficiency, enzyme necessary to prevent GSH exhaustion and depletion (213, 310)

PMID: 124 ZhangRLiangLLiaoKZengHYangXWangXet al

Figure 2 3.1.1 Preclinical foundations and mechanisms Preclinical studies in animal models have established the foundational rationale for this approach