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Arginine interacts with the transcriptional regulators in the mTOR pathway, enhancing T-cell survival and memory T-cell formation (Geiger et al., 2016)

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In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]
People with sensitivities to supplements or those taking L-carnitine derived from certain sources may be at higher risk
