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However, it turns out there is another reason

Nevertheless, the percentage of tumors with a double somatic hit could be underestimated because some tumors also exhibit VUS or uninformative LOH, and the causative effect on the MSI phenotype is uncertain
52,53 Different polyphenol compounds are utilized to prevent and stop the development and prognosis of cancer

In the non-canonical pathway, the Wnt proteins can directly activate the Rho GTPases to modulate the actin cytoskeleton (Salinas and Zou, 2008)
