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The increased metabolic rate is due to the increased muscle protein synthesis and higher lean body mass, associated with testosterone use
This polarization is characterized by a reduction in alternatively activated (M2-like) macrophages, which are typically associated with poor prognosis, and an increase in classically activated (M1-like) macrophages that support adaptive immune responses (130)
10.1016/j.brainresbull.2007.07.011 172 MorenoJ
