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Moreover, clinical research has demonstrated that increased hepatic iron stores and elevated serum ferritin concentrations are common features of various liver diseases 42,43

C677T: G/G: typical function A/G: enzyme function decreased by ~40% A/A: enzyme function decreased by 7080% A1298C: T/T: typical function G/T: slightly decreased function G/G: enzyme function decreased by ~20% Are there other MTHFR variants that matter

doi: 10.1016/0014-5793(73)80755-0 174 MartnezJIGarcaRDGalarzaAM