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Cyanocobalamin is a synthesized form of the vitamin and is the most widely used form of cobalamin in clinical practice because of its relative availability and stability

Earlier research also confirmed that human skin mast cells release histamine in response to certain stimuli (Lowman et al., 1988)
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide

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