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Liao C and Seebeck FP
Consent for publication All participants included in this study provided written informed consent
These findings collectively reveal the previously-unanticipated role of endothelial FAO in heightened retinal vascular leakage, and highlight the potential translational application of GPR30 agonism with Rd to mitigate barrier dysfunction, providing a metabolic regulatory therapeutic strategy for DR
It has low systemic bioavailability but provides pharmacologically active concentrations in colonic tissues, rendering it a good candidate for colorectal cancer management
