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10 These findings highlight the substantial heterogeneity inherent in PD pathophysiology and support RBD-PD as an aggressive clinical subtype
Acetylcysteine is a human drug mainly used as a brand name (Mucomyst 2 and Mucosil-10)
Corroborating this mechanism, preclinical studies have shown that Nox2-deficient mice submitted to the sciatic nerve ligation model of NP develop less mechanical and thermal hypernociception and exhibit reduced production of ROS and proinflammatory cytokines as well as reduced microglia activation [32]
