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Nonetheless, whether the specific mechanism of this is related to the transdifferentiation of VSMCs to a bone-like phenotype, loss in SMC lineage markers, enhanced pro-calcific microRNAs, increased intracellular calcium level, apoptosis, or aberrant DNA damage response (DDR) requires further investigation

The IOM determined that the estimated average requirement (EAR) for protein for adults aged 19-50 years is 0.66 g/kg/day

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For example, a patient with intestinal lymphangiectasia presented with gelatinous transformation of the bone marrow, which was resolved by treatment with a triglyceride-rich diet (326)