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Hypoxia tends to maintain the levels of Hypoxia Inducible Factor (HIF-1), which regulates numerous cellular processes, including angiogenesis and proliferation, and as a result, can cause delayed wound healing ( Extracellular matrix The Extracellular matrix is a key environmental component in healing diabetic wounds, as it acts as a dynamic scaffold for cells and facilitates tissue development and regeneration ( Figure 2 )

Published 2023-7-9 Ferroptosis is a form of programmed cell death characterized by elevated intracellular ferrous ion levels and increased lipid peroxidation

Ascorbic acid is present in 50110 M concentrations in the blood plasma of normal human beings, who also have approximately 520 M dehydroascorbic acid present [91,92]