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In human clinical trials, a study of 90 individuals with atherosclerotic CV disease risk factors suggested that Lactofermented Annurca apple puree was an effective functional food that could effectively control plasma TMAO and HDL-C levels (Tenore et al., 2019)
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During the course of the disease, it can be classified as active and stable

doi:10.1016/j.jep.2020.113434
