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For instance, JDQ443 (KRAS G12C inhibitor), which is currently in phase 3, demonstrated anti-tumor activity with acceptable safety in non-small cell lung cancer (NSCLC)

121 MTF-1 is involved in regulating the zinc-responsive transcription of ZnT1 and ZnT2 and inhibiting the expression of ZIP10, 87,122,123 emphasizing its vital role in zinc homeostasis

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Dai C, Tian E, Hao Z, et al
