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doi: 10.1038/s41574-021-00550-w 63 MiermeisterCPPetersennSBuchfelderMFahlbuschRLdeckeDKHlskenAet al
Targeted therapy approaches are required to treat GBM for enhanced therapy outcome and prolonged survival of GBM patients
To prevent further splicing of the pLEX-3HA-XBP1u transcript by IRE1 which reduces XBP1u protein expression, both splicing sites were mutated (1st: AG TC CG^CA to AG AG CGCA
Wang Y, Yao M, Wang J, et al
