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The carnitine shuttle system described above acts as a buffer for excess mitochondrial acetyl-CoA by transporting the acetyl group into the cytosol while releasing the CoA group in the mitochondrial matrix
Hepatology Communications 6, 780794

A transcrio da CPT-1 , responsvel pela esterificao da L-carnitina, positivamente regulada no fgado de animais com hipertireoidismo, possivelmente justificando a depleo de L-carnitina nesse quadro
