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Sustained reductions in cerebral blood flow may not produce overt infarction but can lead to progressive demyelination, axonal degeneration, and white matter dysfunction

By modulating angiogenesis and vascular integrity, these drugs may contribute to optimizing cerebral blood flow and nutrient delivery to neurons, thereby promoting overall brain health and potentially mitigating neurodegenerative processes

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10.1016/j.ijbiomac.2022.10.173 77 El-SeediH.Abd El-WahedA.YosriN.MusharrafS