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Overall, the MD data was consistent with the markedly different dynamics observed in the cryo-EM 3DVA with the ECDs undergoing substantially greater dynamic motions in the Cagri-AMY 3 R complex than observed in the parallel rAmy-AMY 3 R complex (Supplementary Fig

5i) presented significantly shorter escape latencies than did the control group

Takeaway: Potential utility for age-related sleep-wake cycle disruptions
