l carnitine and depression acetyl-l-carnitine Could a mitochondrial metabolite known as acetyl-L-carnitine (LAC) yield a taking too much l carnitine
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Subjects were, however, functionally sufficient in vitamin B12, the same effect would not be expected in those who are methylation deficient (Semeredi, 2019)

10.1016/j.bmc.2021.116139 248 ShenY
Metabolic plasticity of acute myeloid leukemia

Although the tolerable upper intake limit (UL) for vitamin C in healthy adults is set at 2000 mg, the risk of adverse effects resulting from excess intake appears to be very low
