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Scientific Activity In receptor assays, cagrilintide activates calcitonin-family amylin receptors and the calcitonin receptor, coupling primarily to Gs and cyclic AMP signaling

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It does this by: Stimulating beta-adrenergic receptors in adipose tissue, enhancing fat mobilization Activating AMP-activated protein kinase (AMPK) , a master regulator of cellular energy Increasing fat oxidation (the conversion of stored fat into energy) Reducing fat cell formation in the abdomen and visceral fat regions Improving glucose regulation without affecting insulin sensitivity Critically, AOD-9604 does not increase appetite , fluid retention, or insulin-like growth factor levelsunlike HGH

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