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Moderate deficit works best: 300-500 calorie deficit below maintenance

doi: 10.1186/s13073-020-00741-6 115 JinMZHanRRQiuGZJuXCLouGJinWLet al

Reported pattern in community references: Months 03: body composition shifts through the deficit fat loss with some lean-mass loss expected Months 47: layering cagrilintide adds satiety without adding additional energy-expenditure mechanism body-composition trajectory continues at the prior ratio Months 7+: at maintenance, training stimulus and protein intake dominate body-composition outcomes more than the peptide stack does Whether layering SLU-PP-332 would meaningfully shift the body-composition trajectory by adding an output-side mechanism is unstudied

Angle it so the water runs down the inside wall of the glass