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Studies by Kovalzon et al
A p -value less than 0.05 was considered statistically significant
This deficiency precludes the formulation of definitive, evidence-based recommendations for their therapeutic use at this time
However, the secretion of the anti-diuretic hormone (ADH) in response to increased plasma osmolality occurs at a lower threshold than the threshold for thirst, around 280 mOsm/kg versus 290-295 mOsm/kg respectively ( Bouby and Fernandes 2003
