increase glutathione synthesis Dietary (Phyto)Nutrients for Support Glutathione synthetase - Wikipedia
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Activation of the receptor depends on the binding of glycine and glutamate and AMPA receptor-mediated depolarization of the postsynaptic membrane, which relieves the voltage-dependent channel blocked by Mg 2+ (Bledsoe et al., 2017)

Glutamate Modulation: NMDA receptor antagonists (e.g., memantine) and AMPA receptor antagonists are also used to prevent glutamate-mediated excitotoxicity and reduce seizure frequency

Ferrari D, Wesselborg S, Bauer MK, Schulze-Osthoff K
