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RESUMEN Introduccin: los plaguicidas organoclorados (POC) pueden incrementar la produccin de especies reactivas de oxgeno (ERO)

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The literature reports that melatonin serum levels increase after HI, such as the endogenous neuroprotective response to brain injury 135

The nuclear factor-kappa B (NFB) pathway associated cytokine release is inhibited, hence weakening the signal transduction by IL-1 and nucleotide-binding domain, leucine-richcontaining family, pyrin domaincontaining-3 (NLRP3) inflammasome (Jo et al., 2016)