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It does not establish safety or efficacy for humans, and BPC-157 is not an approved drug or supplement

Importantly, we found that TGFb ligand treatment induced an up-regulation of the SNCA gene upon aSyn overexpression

The upregulated DDX5 then recruits Protein Inhibitor of Activated STAT (PIAS)1, an inhibitory protein of STAT1, thereby blocking STAT1 phosphorylation and activation