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Description
High-quality Omega-3 EPA & DHA
We find strong associations of the melanin biosynthesis gene TYRP1 , ferroptosis related enzyme GPX4 and mitochondrial anion channel ( VDAC1 ) with reduced melanoma-specific survival in TCGA data of cutaneous melanoma

Mechanism of Action: The "Push-Pull" Effect

To mimic ChaC1 overexpression by inducing endogenous ChaC1 high expression, a complementary ChaC1-induction-based screening was performed and revealed proteasome inhibitors (e.g., bortezomib, ixazomib, delanzomib) as potent inducers of endogenous ChaC1 via ATF4-dependent transcriptional activation
