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Gur A, Cevik R, Nas K, Colpan L, Sarac S

In vitro experiments indicate that stimulating FOXO3 expression significantly decreases the generation of ferroptosis-related markers like MDA, suggesting its potential to suppress OA progression (Zhao et al., 2023)
Second, proteostasis disruption involves declined autophagylysosomal and ubiquitinproteasome activity, rendering proteins like syn prone to aggregation and resistant to clearance [62]
