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H.OkuyamaM.NishimotoM.OhguchiM.KimD.et al (2009)
As the upregulation of p21 Cip1/WAF1 protein levels was no longer evident transfecting a dominant-negative form of c-fos (DN/c-fos) in both SkBr3 and Ishikawa cells (Figures 5c and d), we ascertained by chromatin immunoprecipitation assay that LA induces the recruitment of c-fos to the AP1 site located within the p21 Cip1/WAF1 promoter sequence (Figure 5e)
Thus, interference with GSH synthesis in FoB induced an increase in mitochondrial mass without concomitant mtDNA replication
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