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Mao J, Pop VJ, Bath SC, Vader HL, Redman CW, Rayman MP (2016) Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency
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Nonpharmacologic treatment options with published evidence of efficacy in patients with CIPN include chemotherapy dose reduction, discontinuation of the offending chemotherapeutic agent(s), acupuncture, avoiding cold temperatures/maintaining warmth, physical activity, and massaging affected areas ( TABLE 3 )

Another important aspect is the production of high value-added products using less energy consuming enzymatic catalysis connected with microbial lipases
