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Synaptic organization of columnar elements in the lamina of the wild type in Drosophila melanogaster

The accumulation of iron may cause a rise in the intracellular labile iron (II) pool and Fenton reaction, which results in the production of lipid ROS, and ferroptosis

The major pathway for biotransformation of DOX is catalysed by the NADPH-dependent carbonyl reductase, Nitric oxide synthase, cytochrome P-450 reductase, aldo-keto reductase enzymes