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Description
SFN has been shown to alter key mechanisms in vivo and in vitro which impact induction of cell cycle arrest and apoptosis and inhibition of histone deacetylase
In humans, given an oral capsule of 200 mol, the peak plasma was reported to have a Cmax of 0.7 0.2 M at 3 h, with a half-life of 1.9 0.4 h for elimination [115]
Sakuraba, K
It modulated an expression of both metalloproteinases and their inhibitors (TIMP-1 and TIMP-2), improving wound healing and facilitating skin remodeling processes [57]
