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Excessive RCD activation can trigger systemic inflammation due to uncontrolled release of DAMPs and proinflammatory cytokines, leading to cytokine release syndrome and immune-related adverse events (230232)
The dismutation of O 2 . results in the formation of hydrogen peroxide (H 2 O 2 ), which can lead to elevated levels of other potentially harmful reactive oxygen and nitrogen species (ROS, RNS) 2
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And epithelial cancer accounts for 95% of ovarian cancer
