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SOD catalyzes the conversion of superoxide radicals into hydrogen peroxide, which is then further detoxified by catalase and glutathione peroxidase

In 2011, a study described an innovative tumor-targeting therapy that utilizes bone marrow MSCs as a delivery vehicle in combination with silica nanorattle loaded with DOX

doi: 10.1016/j.apt.2017.11.003 41 ChakravartyA.AhmadI.SinghP.Ud Din SheikhM.AalamG.SagadevanS.et al

The blunted inhibition of hexokinase by glucose-6-phosphate is important not only for allowing high rates of upstream glycolysis and ensuring avid glucose uptake from the extracellular space, but also because glucose-6-phosphate may originate from galactose (through glucose-1-phosphate), glycogen (through glycophagy and/or glycogenolysis), and ribose (through the pentose phosphate pathway forming fructose-6-phosphate), (Fig