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Enriched cellular components included the extracellular exosome, extracellular space, and collagen-containing extracellular matrix, indicating active remodeling of the extracellular environment

Compensatory activity of the PC-ME1 metabolic axis underlies differential sensitivity to mitochondrial complex I inhibition

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This is because the loss of ascites through LVP is associated with a reduction in the intra-abdominal pressure, and this tends to exaggerate the pressure difference between the cirrhotic liver and the abdominal cavity, which encourages the rapid refilling of the abdominal cavity