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Trends Endocrinol Metab (2021) 32(7):44462

In addition, it can reduce the release of inflammatory cytokines, including COX-2, prostaglandin E2 (PGE2), inducible nitric oxide synthase (iNOS), and nitric oxide (NO), by inhibiting the NF-B pathway

As current studies indicate, these drugs primarily work by reduced central inflammation and demyelination levels in MS patients through IN delivery

[DOI] [PMC free article] [PubMed] [Google Scholar] Iadecola C, Anrather J
