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Do not self-inject it

Ligresti, vitamin B12 deficiency is found in populations that consume a largely vegan diet, in older people due to malabsorption, and in people with chronic Helicobacter pylori infection

This review included both RCTs and observational studies (N-RCTs, cohort, and case-control) to assess the efficacy of various Vitamin B12 administration routes

Newer research techniques, such as those to image central nervous system inflammation using novel PET imaging (127), may aid diagnosis in the future and provide additional insight into the pathophysiology of persistent symptoms