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To test this hypothesis, we treated T98 sensitive GBM cells with increasing concentrations of an inhibitor of GLUT1 (STF-31 18 ), an inhibitor of GCL (BSO), or the combination of both inhibitors
AKTprotein kinase B
Complex III can also generate O 2 and release it into the intermembrane space where the O 2 traverses through voltage-dependent anion channels (VDACs) into the cytosol and is converted into H 2 O 2 by SOD1
