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Furthermore, in models of Alzheimers disease (AD) and tauopathy, this intervention eliminates amyloid- and pathological tau, leading to improved memory performance

They may also be used for diabetes, hypogonadism, and metabolic disorders

This Review offers a thorough overview of the preclinical models utilized in regenerative neurology for demyelinating diseases, highlighting the rapid progress in biomaterial and gene-editing research, which requires meticulous testing and validation in both in vitro and in vivo environments

Initially, the majority of clinical investigations into KOR antagonists have focused on populations with mood or substance-use disorders, rather than schizophrenia