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Furthermore, recently, immunohistochemistry and RNA-sequencing studies have confirmed that EMT markers are upregulated in OSF tissues, particularly in regions showing dysplasia or carcinoma in situ (Hosur et al., 2021)

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An XAI model was used to predict phenotypes like skin hydration, age, menopausal status, and smoking status based on previously available skin microbiome data, identifying microbial signatures linked to these traits and explaining their relationships with phenotypic variations [140]