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Description
In general, interfering with SCL7A11 expression modulates System X c activity during ferroptosis, thereby regulating cancer cell replication, tissue invasion, and metastasis

, Reference Nussinov2024a)
Pegtibatinase, also known as OT-58 or TVT-058, is a recombinant human CBS catalytic core (amino acids 1413) that has been modified with the addition of polyethylene glycol (PEG) and lacks the CBS autoinhibitory regulatory domain, yielding a constitutively active, predominantly dimeric enzyme

Washington, D.C., American: National Academies Press (US) Copyright 2011, National Academy of Sciences
