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In one study, taking 4,000 mg of omega-3 supplements daily for 12 weeks led to a better GSH-creatine ratio and reduced depressive symptoms in older adults who had a higher risk of developing depression

Effects of oral glutathione on skin appearances: A randomized placebo-controlled study Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB16 Regulation of Tyrosinase Enzyme Activity by Glutathione Peroxidase Mimics Rakesh Kumar Rai, Ramesh Karri, Kshatresh Dutta Dubey, and Gouriprasanna Roy Journal of Agricultural and Food Chemistry 2022 70 (31), 9730-9747 DOI: 10.1021/acs.jafc.2c02359